BIOCOMPATIBLE NONIONIC SURFACTANTS FOR BIOMEDICAL UTILIZATION - DOUBLE-TAILED HYDROCARBON AND OR FLUOROCARBON SYNTHETIC GLYCOLIPIDS

Two classes of double-tailed hydrocarbon and/or fluorocarbon glycolipi ds containing either a gluco- or a galactopyranose residue in their hy drophilic head have been synthesized. The first was obtained upon open ing a maltono- or lactonolactone moiety by the amino group of glycine followed by condensation of the glycine carboxylic function with a dou ble-chain primary amine. The second involves L-lysine in place of glyc ine. Formation of vesicular structures upon conventional treatment was confirmed by preliminary measurements.