HETEROCYCLIC INHIBITORS OF HUMAN-LEUKOCYTE ELASTASE - 3-HYDROXYPYRIDAZOPYRIMIDINE, 3-HYDROXYPYRIDOPYRIMIDINE AND 3-HYDROXYQUINAZOLINE-2,4(1H,3H)DIONE DERIVATIVES

Authors
GROUTAS WC CASTRISOS JC STANGA MA KUANG RZ VENKATARAMAN R EPP JB BRUBAKER MJ CHONG LS
Citation
Wc. Groutas et al., HETEROCYCLIC INHIBITORS OF HUMAN-LEUKOCYTE ELASTASE - 3-HYDROXYPYRIDAZOPYRIMIDINE, 3-HYDROXYPYRIDOPYRIMIDINE AND 3-HYDROXYQUINAZOLINE-2,4(1H,3H)DIONE DERIVATIVES, Bioorganic & medicinal chemistry letters, 3(6), 1993, pp. 1163-1168
Citations number
16
Categorie Soggetti
Chemistry Inorganic & Nuclear","Chemistry Medicinal
Journal title
Bioorganic & medicinal chemistry letters → ACNP
ISSN journal
0960894X
Volume
3
Issue
6
Year of publication
1993
Pages
1163 - 1168
Database
ISI
SICI code
0960-894X(1993)3:6<1163:HIOHE->2.0.ZU;2-S
Abstract
Several heterocyclic compounds derived from 3-hydroxypyridazopyrimidin e-(I), 3-hydroxypyridopyrimidine-(II) and 3-hydroxyquinazoline-2,4(1H, 3H)diones-(III) have been found to be time-dependent irreversible inhi bitors of human leukocyte elastase.