REDUCTION OF DELTA(1)-PYRROLINE-2-CARBOXYLIC ACID TO PROLINE BY AN ESCHERICHIA-COLI PROLINE AUXOTROPH

Authors
LEWIS ML MARTIN SL ROWE CJ SUTHERLAND JD WILSON EJ WRIGHT MC
Citation
Ml. Lewis et al., REDUCTION OF DELTA(1)-PYRROLINE-2-CARBOXYLIC ACID TO PROLINE BY AN ESCHERICHIA-COLI PROLINE AUXOTROPH, Bioorganic & medicinal chemistry letters, 3(6), 1993, pp. 1189-1192
Citations number
10
Categorie Soggetti
Chemistry Inorganic & Nuclear","Chemistry Medicinal
Journal title
Bioorganic & medicinal chemistry letters → ACNP
ISSN journal
0960894X
Volume
3
Issue
6
Year of publication
1993
Pages
1189 - 1192
Database
ISI
SICI code
0960-894X(1993)3:6<1189:RODATP>2.0.ZU;2-1
Abstract
A new synthesis of DELTA1-pyrroline-2-carboxylic acid 2 and various is otopomers is described; the conversion of 2 to proline by Escherichia coli is shown to proceed by a direct reduction.