SAR OF COCAINE - FURTHER EXPLORATION OF STRUCTURAL VARIATIONS AT THE C-2 CENTER PROVIDES COMPOUNDS OF SUBNANOMOLAR BINDING POTENCY

Authors
KOZIKOWSKI AP ROBERTI M JOHNSON KM BERGMANN JS BALL RG
Citation
Ap. Kozikowski et al., SAR OF COCAINE - FURTHER EXPLORATION OF STRUCTURAL VARIATIONS AT THE C-2 CENTER PROVIDES COMPOUNDS OF SUBNANOMOLAR BINDING POTENCY, Bioorganic & medicinal chemistry letters, 3(6), 1993, pp. 1327-1332
Citations number
15
Categorie Soggetti
Chemistry Inorganic & Nuclear","Chemistry Medicinal
Journal title
Bioorganic & medicinal chemistry letters → ACNP
ISSN journal
0960894X
Volume
3
Issue
6
Year of publication
1993
Pages
1327 - 1332
Database
ISI
SICI code
0960-894X(1993)3:6<1327:SOC-FE>2.0.ZU;2-P
Abstract
Syntheses of a variety of new analogues of cocaine are reported togeth er with their binding affinities and dopamine uptake inhibition activi ties. The present work further expands the SAR data base for cocaine.