REACTIVITY OF AN EPOXY-SPIROKETAL WITHIN AVERMECTIN B2A

Authors
NEWBOLD RC SHIH TL MROZIK H FISHER MH
Citation
Rc. Newbold et al., REACTIVITY OF AN EPOXY-SPIROKETAL WITHIN AVERMECTIN B2A, Tetrahedron letters, 34(24), 1993, pp. 3825-3828
Citations number
7
Categorie Soggetti
Chemistry Inorganic & Nuclear
Journal title
Tetrahedron letters → ACNP
ISSN journal
00404039
Volume
34
Issue
24
Year of publication
1993
Pages
3825 - 3828
Database
ISI
SICI code
0040-4039(1993)34:24<3825:ROAEWA>2.0.ZU;2-B
Abstract
Interesting reactivities have been observed upon reaction of epoxy-spi roketal 1 with a variety of dimethyl-aluminum sulfides, and are compar ed with results obtained upon reaction of the same epoxide 1 with diet hyl aluminum cyanide. These chemical modifications provide access to n ovel avermectin B2a analogs possessing interesting biological properti es.