Drug injectors have become the second largest HIV transmission categor
y in Argentina and Brazil, as is the case in many pattern I countries,
making up more than one-quarter of all AIDS cases reported by 1991. H
IV seroprevalence data suggest that the expanding proportion of AIDS c
ases attributable to drug injection stems from an absolute increase in
the number of AIDS cases among drug injectors, and is not merely refl
ective of a decline in the proportion of cases reported in other trans
mission categories. Results of a review of studies in Argentina and Br
azil indicate that HIV seroprevalence is increasing rapidly, contrary
to the situation in some pattern I countries in which HIV seroprevalen
ce among drug injectors is either stably high or increasing only sligh
tly. Also contrary to most pattern I countries, cocaine rather than he
roin is the injected drug of choice in Argentina and Brazil. Given tha
t injectors of cocaine are more likely to be HIV infected than are her
oin injectors, differences in the type of drug injected between countr
ies may have distinct epidemiological consequences on the spread of HI
V.