Rw. Allinson et al., FLUORESCEIN ANGIOGRAPHIC APPEARANCE OF DALEN-FUCHS NODULES IN SYMPATHETIC OPHTHALMIA, Annals of ophthalmology, 25(4), 1993, pp. 152-156
A case of sympathetic ophthalmia is presented in which a single lesion
located posteriorly at the level of the retinal pigment epithelium ca
used a serous macular detachment. We believe that this lesion represen
ted an atypical Dalen-Fuchs nodule. Most reports of the fluorescein an
giographic appearance of Dalen-Fuchs nodules describe multiple sites o
f choroidal leakage during the early phases, which may coalesce during
the late phases of the angiogram. The lesion we detected was hypofluo
rescent in early phases of the fluorescein angiogram and showed late s
taining. The early hypofluorescence seen in the lesion may be explaine
d by an intact retinal pigment epithelium over the presumed Dalen-Fuch
s nodule, blockage of choroidal fluorescence by the nodule, and areas
of granulomatous inflammation in the inner choroid and choriocapillari
s. The staining in the late phases of the fluorescein angiogram may be
explained by accumulation of fluorescein into the presumed Dalen-Fuch
s nodule.