OLIGODEOXYRIBONUCLEOTIDES CONTAINING 2'-AMINO-2'-DEOXYPYRIMIDINE NUCLEOSIDES

Authors
KUZNETSOVA LG ROMANOVA EA VOLKOV EM TASHLITSKY VN ORETSKAYA TS KRYNETSKAYA NF SHABAROVA ZA
Citation
Lg. Kuznetsova et al., OLIGODEOXYRIBONUCLEOTIDES CONTAINING 2'-AMINO-2'-DEOXYPYRIMIDINE NUCLEOSIDES, Bioorganiceskaa himia, 19(4), 1993, pp. 455-466
Citations number
19
Categorie Soggetti
Chemistry Inorganic & Nuclear
Journal title
Bioorganiceskaa himia → ACNP
ISSN journal
01323423
Volume
19
Issue
4
Year of publication
1993
Pages
455 - 466
Database
ISI
SICI code
0132-3423(1993)19:4<455:OC2N>2.0.ZU;2-#
Abstract
The synthesis, by means of the standard phosphoramidite chemistry, of modified oligodeoxynucleotides (5-20 residues) containing 2'-amino-2'- deoxypyrimidine nucleosides has been carried out, and their ability to form duplexes with complementary DNA has been investigated. A high re activity of such compounds in N-acylation was shown.