HOMOCHIRAL ORGANOELEMENT ANALOGS OF NATURAL COMPOUNDS .3. BIOCATALYTIC METHOD FOR PRODUCTION OF FLUOROSUBSTITUTED (R)-PHENYLALANINES AND (S)-PHENYLALANINES, (S, R)-PHENYLSERINES AND (R, S)-PHENYLSERINES

Citation
Va. Soloshonok et al., HOMOCHIRAL ORGANOELEMENT ANALOGS OF NATURAL COMPOUNDS .3. BIOCATALYTIC METHOD FOR PRODUCTION OF FLUOROSUBSTITUTED (R)-PHENYLALANINES AND (S)-PHENYLALANINES, (S, R)-PHENYLSERINES AND (R, S)-PHENYLSERINES, Bioorganiceskaa himia, 19(4), 1993, pp. 478-483
Citations number
17
Categorie Soggetti
Chemistry Inorganic & Nuclear
Journal title
ISSN journal
01323423
Volume
19
Issue
4
Year of publication
1993
Pages
478 - 483
Database
ISI
SICI code
0132-3423(1993)19:4<478:HOAONC>2.0.ZU;2-2
Abstract
A convenient method for production of homochiral threo-beta-(4-fluorop henyl)serine, 2-fluoro-, 3-fluoro-, 4-fluoro- and 2, 3, 4, 5, 6-pentaf luorophenylalanines was developed by means of the enantioselective hyd rolysis of their N-phenylacetyl derivatives with penicillin acylase (E C 3.5.1.11) from Escherichia coli.