HOMOCHIRAL ORGANOELEMENT ANALOGS OF NATURAL COMPOUNDS .3. BIOCATALYTIC METHOD FOR PRODUCTION OF FLUOROSUBSTITUTED (R)-PHENYLALANINES AND (S)-PHENYLALANINES, (S, R)-PHENYLSERINES AND (R, S)-PHENYLSERINES
Va. Soloshonok et al., HOMOCHIRAL ORGANOELEMENT ANALOGS OF NATURAL COMPOUNDS .3. BIOCATALYTIC METHOD FOR PRODUCTION OF FLUOROSUBSTITUTED (R)-PHENYLALANINES AND (S)-PHENYLALANINES, (S, R)-PHENYLSERINES AND (R, S)-PHENYLSERINES, Bioorganiceskaa himia, 19(4), 1993, pp. 478-483
A convenient method for production of homochiral threo-beta-(4-fluorop
henyl)serine, 2-fluoro-, 3-fluoro-, 4-fluoro- and 2, 3, 4, 5, 6-pentaf
luorophenylalanines was developed by means of the enantioselective hyd
rolysis of their N-phenylacetyl derivatives with penicillin acylase (E
C 3.5.1.11) from Escherichia coli.