Mt. Massie et al., NORMOTHERMIC RETROGRADE CONTINUOUS CARDIOPLEGIA FOR MYOCARDIAL PROTECTION DURING CARDIOPULMONARY BYPASS - A MODIFIED TECHNIQUE, Texas Heart Institute journal, 20(2), 1993, pp. 89-93
Normothermic retrograde continuous cardioplegia is a revolutionary dev
elopment for myocardial preservation in cardiac surgery. Despite excel
lent reports regarding this technique, the surgical community has expr
essed concern over technical problems encountered. The method of normo
thermic retrograde continuous cardioplegia in current use requires bot
h large total crystalloid volumes and large potassium loads to deliver
adequate cardioplegia. We have developed a technique that eliminates
these problems. The heart is stopped by an initial infusion of normoth
ermic cardioplegic solution through a coronary sinus catheter The infu
sate is then converted to normothermic pump blood. Small boluses of po
tassium chloride are added intermittently to maintain cardiac arrest.
We applied this technique to 35 patients undergoing cardiac valve surg
ery The average volume of crystalloid cardioplegia required was 125 mL
(range, 40 to 155 mL), and the average total potassium load was 52 mE
q (range, 2 to 100 mEq). Clinically significant sequelae were noted in
4 patients (11%), and 1 (3%) died of pneumonia on the 28th postoperat
ive day The method we describe is a safe and effective alternative to
the current technique of normothermic retrograde continuous cardiopleg
ia and offers both physiologic and technical advantages to patients un
dergoing cardiac valve procedures.