We report three patients undergoing keratoepithelioplasty using donor
limbal tissue. All three had significant vascularization of the recipi
ent bed and all three had inflammatory reactions with apparent partial
replacement of the donor epithelium with host epithelium. Limbal tran
splantation, which is likely to include significant numbers of donor L
angerhans' cells, may well increase the risk of graft failure in kerat
oepithelioplasty.