Soy fiber has been shown to reduce the duration of watery stools durin
g acute diarrhea caused by bacterial and viral pathogens in underdevel
oped countries, A randomized blinded clinical trial was conducted with
middle-class American children to assess the efficacy of soy fiber-su
pplemented infant formula. Stool characteristics, intake, and weight w
ere recorded. Infants >6 months of age (n = 44) fed soy fiber-suppleme
nted formula (Isomil DF(R)) had a significantly shorter estimated medi
an duration of diarrhea (9.7 hours vs. 23.1 hours) than those fed soy
formula (Isomil(R)). The use of fiber-supplemented soy formula may red
uce the duration of diarrheal symptoms in U.S. infants more than 6 mon
ths of age with acute diarrhea.