Ep. Theakston et al., TRANSFUSION-TRANSMITTED YERSINIA-ENTEROCOLITICA INFECTION IN NEW-ZEALAND, Australian and New Zealand Journal of Medicine, 27(1), 1997, pp. 62-67
Aims: To update and summarise cases of transfusion-transmitted Yersini
a enterocolitica infection in New Zealand and to evaluate critically s
uggested methods to reduce this rare but frequently fatal complication
of blood transfusion. Methods: Case reports of four recent transfusio
n-transmitted Y. enterocolitica infections in New Zealand are given an
d previous reports reviewed. Literature review and evaluation of propo
sed methods to decrease the incidence of transfusing yersinia contamin
ated blood. Results: There have been eight cases of transfusion-transm
itted Y. enterocolitica infection in New Zealand in the past five year
s. Four of the five deaths have been directly caused by the transfusio
n. This gives a transfusion incidence rate of one: 65,000 and a fatali
ty rate of one: 104,000 units transfused. This fatality rate is more t
han 80 times higher than that reported in the United States. Conclusio
ns: Why the incidence of transfusion-transmitted yersinia is so high i
s not clear, since we do not store blood as long as many other countri
es, particularly the United States. In Auckland, however the cases cam
e at a time when the number of yersinia isolates from the community is
reported to be rising.Many suggestions for the prevention of this pro
blem have been put forward reflecting the fact that there is as yet no
perfect solution. Those which are easy to implement and cheap to perf
orm are largely already in place and investigation is continuing into
the other alternatives.