This report describes the occurrence of acute transient myopia in a pa
tient treated with sulfonamide. We followed this patient by performing
A-scan ultrasonographic ocular measurements documenting the anterior
chamber depth, lens thickness, and axial length during the acute and c
onvalescent periods. The outstanding feature in this case was the docu
mented ultrasonographically significant reduction of the anterior cham
ber depth combined with lens thickening. This could be caused by a for
ward displacement of the lens as a result of allergic ciliary body ede
ma and rotation. These changes could explain the mechanism of drug-ind
uced transient myopia.