ECTOPIC MEDULLARY HEMATOPOIESIS AS A CAUSE OF ASCITES IN AGNOGENIC MYELOID METAPLASIA - CASE-REPORT AND REVIEW OF THE LITERATURE

Authors
KNOBEL B MELAMUD E VIRAG I MEYTES D
Citation
B. Knobel et al., ECTOPIC MEDULLARY HEMATOPOIESIS AS A CAUSE OF ASCITES IN AGNOGENIC MYELOID METAPLASIA - CASE-REPORT AND REVIEW OF THE LITERATURE, Acta haematologica, 89(2), 1993, pp. 104-107
Citations number
21
Categorie Soggetti
Hematology
Journal title
Acta haematologica → ACNP
ISSN journal
00015792
Volume
89
Issue
2
Year of publication
1993
Pages
104 - 107
Database
ISI
SICI code
0001-5792(1993)89:2<104:EMHAAC>2.0.ZU;2-B
Abstract
We report an unusual case of a 44-year-old female patient with 'malign ant' ascites caused by ectopic foci of extramedullary hematopoiesis in the course of agnogenic myeloid metaplasia. The patient had suffered also from severe Coombs-positive acquired hemolytic anemia and had bee n splenectomized. Two years after splenectomy, ascites caused by perit oneal implants of hematopoietic tissue appeared. The ascites responded promptly to treatment with busulfan and hydroxyurea. The clinical pic ture, treatment and a review of the literature concerning the mechanis ms of this uncommon evolution are discussed.