ANTIBIOTIC-RESISTANCE IN 2187 STRAINS ISOLATED IN MALI BETWEEN 1980 AND 1991

This study is about evolution and actual state of antibiotic resistanc e of 2,187 bacterial strains collected from 1980 to 1991. It consisted in performing sensitivity tests with bacteria isolated from patients during this period. For S. aureus, gentamicin, macrolides and related were most effective but about 50 % of strains were resistant to oxacil lin. Cefotaxime, gentamicin, nalidixic acid, nitrofurans and nitroxoli n were most effective against E. coli. For Enterobacter spp, cefotaxim e, gentamicin, nalidixic acid and colistin were most effective. Finall y for P. aeruginosa, colistin was fully active and gentamicin active q uite well. In general, resistance was stable, but it mainly developed to oxacillin, tetracyclines and cotrimoxazole.