PULMONARY INFECTION WITH MYCOBACTERIUM-MALMOENSE COMPLICATED BY ASPERGILLOMA

A 49 year old man was medically treated, first in 1986 and then in 198 8, for atypical primary pulmonary infection caused by Mycobacterium ma lmoense. Since no clinical or bacteriological improvement of both smea r and culture was observed, upper right bilobectomy was performed in d ecember 1988. Oral treatment with rifabutin, clofazimine, ethambutol a nd isoniazid was clinically and bacteriologically successful in May 19 89. In 1990, Aspergillus flavus infection developed in a sequeleae cav ity located in the posterior segment of the upper left lobe. To our kn owledge the Mycobacterium malmoense-Aspergillus flavus association has not yet been described.