HLA DR4 IS ASSOCIATED WITH THE DEVELOPMENT OF MULTIPLE BASAL-CELL CARCINOMAS AND MALIGNANT-MELANOMA

Authors
CZARNECKI D NICHOLSON I TAIT B NASH C
Citation
D. Czarnecki et al., HLA DR4 IS ASSOCIATED WITH THE DEVELOPMENT OF MULTIPLE BASAL-CELL CARCINOMAS AND MALIGNANT-MELANOMA, Dermatology, 187(1), 1993, pp. 16-18
Citations number
17
Categorie Soggetti
Dermatology & Venereal Diseases
Journal title
Dermatology → ACNP
ISSN journal
10188665
Volume
187
Issue
1
Year of publication
1993
Pages
16 - 18
Database
ISI
SICI code
1018-8665(1993)187:1<16:HDIAWT>2.0.ZU;2-2
Abstract
An association between HLA DR4 and the development of multiple basal c ell carcinomas (BCC) and malignant melanoma (MM) was detected in south ern Australia. There were highly significant differences in HLA DR fre quencies between patients with multiple BCCs and MM and matched patien ts with multiple BCCs only. These findings suggest that hereditary fac tors associated with the HLA system influence what types of multiple s kin cancers people develop.