A PILOT CLINICAL-TRIAL OF THE ANGIOTENSIN-CONVERTING ENZYME-INHIBITORCERANAPRIL IN ALZHEIMER-DISEASE

Authors
SUDILOVSKY A CUTLER NR SRAMEK JJ WARDLE T VEROFF AE MICKELSON W MARKOWITZ J REPETTI S
Citation
A. Sudilovsky et al., A PILOT CLINICAL-TRIAL OF THE ANGIOTENSIN-CONVERTING ENZYME-INHIBITORCERANAPRIL IN ALZHEIMER-DISEASE, Alzheimer disease and associated disorders, 7(2), 1993, pp. 105-111
Citations number
21
Categorie Soggetti
Neurosciences,Pathology
Journal title
Alzheimer disease and associated disorders → ACNP
ISSN journal
08930341
Volume
7
Issue
2
Year of publication
1993
Pages
105 - 111
Database
ISI
SICI code
0893-0341(1993)7:2<105:APCOTA>2.0.ZU;2-O
Abstract
This pilot clinical trial was a 15-week, double-blind, controlled, thr ee-way crossover study evaluating cognitive effects of ceranapril in s ubjects with dementia of the Alzheimer type (age range 50-75 years). C omputerized (CNTB) and noncomputerized cognitive test batteries reveal ed no significant results (p > 0.05). On further analysis of the data, however, a study of longer duration and/or higher dosages may be warr anted.