An end-to-end anastomosis was done in the center of a 5-cm devasculari
zed jejunal segment in 5 control laboratory rabbits and 14 experimenta
l rabbits. A second group consisted of 5 control animals and 11 experi
mental animals having end-to-end jejunojejunostomy in the center of a
10-cm devascularized jejunal segment. In the experimental animals, the
anastomosis was wrapped circumferentially by a vascularized omental p
edicle. Anastomotic leaks or fistulas developed in five 10-cm controls
(100%), five 5-cm controls (100%), nine 10-cm omental wraps (82%), an
d four 5-cm omental wraps (29%). The remaining animals had strictures
of various degrees. Injection of methylene blue into the omental vesse
ls showed perfusion to the mucosa from the omentum. The difference bet
ween the 10-cm segment and the 5-cm segment indicates some limitation
to the available blood flow from the omentum. The anastomotic strictur
ing was due to ischemic injury before reperfusion by ingrowth of oment
al vessels. A vascularized omental pedicle wrap can augment blood flow
; however, the time required for neovascular ingrowth allows ischemic
mucosal injury if there is no other available blood supply.