ENDOGENEOUS CORTISOL EXERTS ANTIEMETIC EFFECT SIMILAR TO THAT OF EXOGENOUS CORTICOSTEROIDS

Authors
HURSTI TJ FREDRIKSON M STEINECK G BORJESON S FURST CJ PETERSON C
Citation
Tj. Hursti et al., ENDOGENEOUS CORTISOL EXERTS ANTIEMETIC EFFECT SIMILAR TO THAT OF EXOGENOUS CORTICOSTEROIDS, British Journal of Cancer, 68(1), 1993, pp. 112-114
Citations number
9
Categorie Soggetti
Oncology
Journal title
British Journal of Cancer → ACNP
ISSN journal
00070920
Volume
68
Issue
1
Year of publication
1993
Pages
112 - 114
Database
ISI
SICI code
0007-0920(1993)68:1<112:ECEAES>2.0.ZU;2-H
Abstract
Lower pre-chemotherapy night time cortisol excretion predicted more se vere cisplatin induced nausea and vomiting in 42 ovarian cancer patien ts receiving ondansetron as a single antiemetic agent. Dexamethasone a dministration added to the antiemetic effect of ondansetron principall y in patients who had low excretion of cortisol.