S. Colombatto et Ma. Grillo, OKADAIC ACID INHIBITS INSULIN STIMULATION OF BOTH ORNITHINE DECARBOXYLASE AND SPERMIDINE TRANSPORT IN HEPATOCYTE CULTURES, International Journal of Biochemistry, 25(5), 1993, pp. 697-700
1. Okadaic acid inhibited basal ODC activity in rat hepatocytes in cul
ture and prevented any increase in ODC activity and in the rate of spe
rmidine uptake promoted by both insulin and hypotonicity. 2. The incre
ase promoted by AIB was not counteracted by okadaic acid.