Human infections due to Aspergillosis Fungi are unusual and occur pref
erentially in defenceless patients. Nonetheless, our patient, a seed-s
hop owner, was not immuno-depressed and became infected by inhalating
or chewing the seeds. Moreover, the aspergillosis was situated in the
sphenoidal sinus, which is extremely unusual. In fact, the initial pse
udo tumoral and misleading appearance justified a surgical biopsy whic
h revealed a black << truffle >> suggestive of aspergillosis and was c
onfirmed by anatomo-pathology.