PREPARATION AND CHARACTERIZATION OF SPHERICAL POLYMER PACKINGS FROM N,N-DIALKYLACRYLAMIDE FOR REVERSED-PHASE LIQUID-CHROMATOGRAPHY

Chemically stable, totally organic polymer packings were prepared usin g newly developed N,N-dialkylacrylamides and their chromatographic pro perties were examined. The polymer packings were composed of N-methyl N-octadecylacrylamide as a hydrophobic moiety and N,N'-diacrylo-N,N'-d ibutyl-1,6-diaminohexane as a crosslinking monomer. The melting points of both monomers were much lower than those of conventional acrylamid e and methacrylamide monomers e.g., N-octadecylmethacrylamide, N,N'-bu tylenebis(methacrylamide) and N,N'-methylenebis(acrylamide). This prop erty increased misicibility among the monomers and mode possible suspe nsion copolymerization without use of a third solvent, which would hav e lowered the mechanical strength of the polymer obtained. The hydroph obicity of the particles prepared by suspension copolymerization was c ontrolled by the monomer ratio in the polymerization. In the liquid ch romatography, the column with polymer particles showed normal reversed -phase liquid chromatographic separations for alkanes, alcohols and ar omatic hydrocarbons. In addition, the packings did not show abnormal a dsorption for ionic substances because they were ion free, and showed no peak tailing for carbonyl compounds because of their lack of amide protons.