SEVERE PHENYTOIN-INDUCED BONE-MARROW DEPRESSION AND AGRANULOCYTOSIS TREATED WITH HUMAN RECOMBINANT GRANULOCYTE-MACROPHAGE COLONY-STIMULATING FACTOR - CASE-REPORT
A. Rawanduzy et al., SEVERE PHENYTOIN-INDUCED BONE-MARROW DEPRESSION AND AGRANULOCYTOSIS TREATED WITH HUMAN RECOMBINANT GRANULOCYTE-MACROPHAGE COLONY-STIMULATING FACTOR - CASE-REPORT, Journal of neurosurgery, 79(1), 1993, pp. 121-124
An unusual instance of severe and potentially lethal depression of the
bone marrow is described as a result of the administration of phenyto
in for seizure prophylaxis. The patient was treated successfully by pr
ompt cessation of phenytoin and intravenous administration of human re
combinant granulocyte-macrophage colony-stimulating factor.