SEVERE PHENYTOIN-INDUCED BONE-MARROW DEPRESSION AND AGRANULOCYTOSIS TREATED WITH HUMAN RECOMBINANT GRANULOCYTE-MACROPHAGE COLONY-STIMULATING FACTOR - CASE-REPORT

Authors
RAWANDUZY A SARKIS A ROVIT RL
Citation
A. Rawanduzy et al., SEVERE PHENYTOIN-INDUCED BONE-MARROW DEPRESSION AND AGRANULOCYTOSIS TREATED WITH HUMAN RECOMBINANT GRANULOCYTE-MACROPHAGE COLONY-STIMULATING FACTOR - CASE-REPORT, Journal of neurosurgery, 79(1), 1993, pp. 121-124
Citations number
30
Categorie Soggetti
Neurosciences,Surgery
Journal title
Journal of neurosurgery → ACNP
ISSN journal
00223085
Volume
79
Issue
1
Year of publication
1993
Pages
121 - 124
Database
ISI
SICI code
0022-3085(1993)79:1<121:SPBDAA>2.0.ZU;2-0
Abstract
An unusual instance of severe and potentially lethal depression of the bone marrow is described as a result of the administration of phenyto in for seizure prophylaxis. The patient was treated successfully by pr ompt cessation of phenytoin and intravenous administration of human re combinant granulocyte-macrophage colony-stimulating factor.