BACKGROUND. Numerous approaches are used to treat keloids, but none is
ideal for all scars and recurrence after treatment is frequent. OBJEC
TS. The purpose of this study was to evaluate the efficacy of cryother
apy for treatment of these scars. METHODS. Sixty-five lesions of vario
us sizes and ages were treated with a hand-held liquid nitrogen spray
unit, freeze times and number of sessions varied. Scar volume was meas
ured before and after treatment. RESULTS. Complete flattening was achi
eved in 48 scars (73%), most of which were less than 2 years old. Unac
ceptable responses were seen in six scars. No recurrence was seen duri
ng follow-ups ranging from 17 to 42 months. Side effects were limited
to hypopigmentation and slight to moderate atrophy in three cases. CON
CLUSION. Cryotherapy is an effective, low-risk approach to keloid trea
tment associated with a low rate of recurrence.