A RECENTLY RECOGNIZED ENTITY ASSOCIATED WITH THE TREATMENT OF ACUTE PROMYELOCYTIC LEUKEMIA - THE RETINOIC ACID SYNDROME

Authors
MARINAKIS T PAPADIMITRIOU CA KOUFOS C FERTAKIS A
Citation
T. Marinakis et al., A RECENTLY RECOGNIZED ENTITY ASSOCIATED WITH THE TREATMENT OF ACUTE PROMYELOCYTIC LEUKEMIA - THE RETINOIC ACID SYNDROME, Haematologica, 78(3), 1993, pp. 192-194
Citations number
23
Categorie Soggetti
Hematology
Journal title
Haematologica → ACNP
ISSN journal
03906078
Volume
78
Issue
3
Year of publication
1993
Pages
192 - 194
Database
ISI
SICI code
0390-6078(1993)78:3<192:ARREAW>2.0.ZU;2-X
Abstract
All-trans-retinoic acid is an effective induction treatment for acute promyelocytic leukemia. Although retinoic acid is well tolerated by th e majority of patients with this disease, a potentially fatal complica tion of this kind of treatment has been reported: <<the retinoic acid syndrome>>. We describe this syndrome, which occurred in one of our pa tients and was successfully treated by the administration of dexametha sone.