1ST SYNTHESIS OF THE CYTOTOXIC AND ANTIFUNGAL C-14 AMINE (2S,3E,5Z)-2-AMINO-3,5,13-TETRADECATRIENE ISOLATED FROM THE NEW-ZEALAND ASCIDIAN PSEUDODISTOMA-NOVAEZELANDIAE

Authors
ENDERS D FINKAM M
Citation
D. Enders et M. Finkam, 1ST SYNTHESIS OF THE CYTOTOXIC AND ANTIFUNGAL C-14 AMINE (2S,3E,5Z)-2-AMINO-3,5,13-TETRADECATRIENE ISOLATED FROM THE NEW-ZEALAND ASCIDIAN PSEUDODISTOMA-NOVAEZELANDIAE, Liebigs Annalen der Chemie, (5), 1993, pp. 551-555
Citations number
16
Categorie Soggetti
Chemistry
Journal title
Liebigs Annalen der Chemie → ACNP
ISSN journal
01702041
Issue
5
Year of publication
1993
Pages
551 - 555
Database
ISI
SICI code
0170-2041(1993):5<551:1SOTCA>2.0.ZU;2-M
Abstract
The synthesis of (2S,3E,5Z)-2-amino-3,5,13-tetradecatriene [(S-1)] wit h high enantiomeric purity in excellent overall yield is described. In the crucial step the stereogenic center was generated by nucleophilic addition of tert-butyl carbamate to a planar-chiral tetracarbonyliron (1+) complex.