PALLADIUM-CATALYZED REACTIONS IN AQUEOUS-MEDIA - AN EFFICIENT REMOVALOF ALLYLOXYCARBONYL PROTECTING GROUP FROM OXYGEN AND NITROGEN

Authors
GENET JP BLART E SAVIGNAC M LEMEUNE S PARIS JM
Citation
Jp. Genet et al., PALLADIUM-CATALYZED REACTIONS IN AQUEOUS-MEDIA - AN EFFICIENT REMOVALOF ALLYLOXYCARBONYL PROTECTING GROUP FROM OXYGEN AND NITROGEN, Tetrahedron letters, 34(26), 1993, pp. 4189-4192
Citations number
28
Categorie Soggetti
Chemistry Inorganic & Nuclear
Journal title
Tetrahedron letters → ACNP
ISSN journal
00404039
Volume
34
Issue
26
Year of publication
1993
Pages
4189 - 4192
Database
ISI
SICI code
0040-4039(1993)34:26<4189:PRIA-A>2.0.ZU;2-H
Abstract
The Allyloxycarbonyl (Alloc) moiety can be removed smoothly and select ively in good yield (70-99%) from allylic esters, carbamates and carbo nates by aqueous Pd (0) catalyzed allyl transfer to diethylamine as th e accepting nucleophile. The method has been successfully used for dep rotection of a wide range of secondary amines.