Retrospective analysis of 4886 adults undergoing coronary arteriograph
y for evaluation of angina between October 1988 and December 1991, rev
ealed coronary artery fistulae in eight patients (all men, aged 36-69
years). No murmur was audible in any of these eight patients. Associat
ed significant coronary artery disease was detected in five patients.
The feeder arteries to the fistula were both the left main coronary ar
tery and the left anterior desending artery (LAD) in two, the LAD in s
ix, and the right coronary artery in two patients. The fistula termina
ted in the pulmonary artery in seven patients and in the right atrium
in one patient. Successful operative treatment (coronary artery bypass
grafting and ligation of the fistula) was undertaken in four patients
with severe obstructive coronary artery disease with satisfactory res
ults. Follow-up for up to 2 years of the three patients with coronary
artery fistula and no associated coronary artery disease who did not u
ndergo surgery revealed continuing good prognosis. We conclude that co
ronary artery fistula in adults is a distinct, though rare (incidence
in present series 0.11%) entity, without audible murmur, commonly asso
ciated with coronary artery obstructive disease, and that the diagnosi
s is mostly incidental during routine coronary arteriography.