LETHAL FIBROSARCOMA COMPLICATING RADIATION-THERAPY FOR BENIGN GLOMUS-JUGULARE TUMOR

Citation
Ak. Lalwani et al., LETHAL FIBROSARCOMA COMPLICATING RADIATION-THERAPY FOR BENIGN GLOMUS-JUGULARE TUMOR, The American journal of otology, 14(4), 1993, pp. 398-402
Citations number
39
Categorie Soggetti
Otorhinolaryngology
ISSN journal
01929763
Volume
14
Issue
4
Year of publication
1993
Pages
398 - 402
Database
ISI
SICI code
0192-9763(1993)14:4<398:LFCRFB>2.0.ZU;2-N
Abstract
Radiation therapy for temporal bone paragangliomas has been advocated by many authors, but remains controversial. Radiation has little direc t effect on the tumor cells, and diminution in tumor size is seldom se en. The main reason radiation therapy is recommended over surgical man agement of glomus tumors is its purported lower complication rate. We report a case of a lethal radiation-induced fibrosarcoma presenting 15 years following irradiation for a benign glomus jugulare tumor. Radia tion-induced malignancies are rare, but are lethal when they occur. In experienced hands, surgical removal of glomus jugulare tumors carries a limited morbidity and virtually no mortality. In our opinion, the p ossibility of inducing a secondary life-threatening malignancy must be seriously considered when discussing therapeutic options with otherwi se healthy individuals who are expected to survive 10 or more years af ter treatment.