Ak. Lalwani et al., LETHAL FIBROSARCOMA COMPLICATING RADIATION-THERAPY FOR BENIGN GLOMUS-JUGULARE TUMOR, The American journal of otology, 14(4), 1993, pp. 398-402
Radiation therapy for temporal bone paragangliomas has been advocated
by many authors, but remains controversial. Radiation has little direc
t effect on the tumor cells, and diminution in tumor size is seldom se
en. The main reason radiation therapy is recommended over surgical man
agement of glomus tumors is its purported lower complication rate. We
report a case of a lethal radiation-induced fibrosarcoma presenting 15
years following irradiation for a benign glomus jugulare tumor. Radia
tion-induced malignancies are rare, but are lethal when they occur. In
experienced hands, surgical removal of glomus jugulare tumors carries
a limited morbidity and virtually no mortality. In our opinion, the p
ossibility of inducing a secondary life-threatening malignancy must be
seriously considered when discussing therapeutic options with otherwi
se healthy individuals who are expected to survive 10 or more years af
ter treatment.