Ca. Derby et al., CORRELATES OF POSTMENOPAUSAL ESTROGEN USE AND TRENDS THROUGH THE 1980S IN 2 SOUTHEASTERN NEW-ENGLAND COMMUNITIES, American journal of epidemiology, 137(10), 1993, pp. 1125-1135
Correlates and prevalence of current postmenopausal estrogen use were
examined in two southeastern New England communities for the period 19
81 through 1990. Data were obtained from five biennial cross-sectional
household health surveys, with current use of postmenopausal estrogen
determined by inspection of medication bottles. Analysis included 3,2
79 women aged 40-64 years, of whom 2,215 (67.6%) were postmenopausal.
The prevalence of estrogen use among all postmenopausal women increase
d from 5.3% (95% confidence interval (Cl) 3.2-7.4) in 1981-1982 to 10.
9% (95% Cl 7.5-14.4) in 1989-1990. Among women with surgical menopause
, prevalence increased from 11.4% (95% Cl 6.6-16.2) to 20.3% (95% Cl 1
3.6-27.0), while use among women with natural menopause increased from
1.5% (95% Cl 0.04-2.9) to 3.5% (95% Cl 0.74-6.2). Logistic regression
was used to compute age-adjusted prevalence of estrogen use according
to demographic characteristics and cardiovascular risk factors. Postm
enopausal estrogen use was positively associated with income, and a po
sitive trend with education was suggested. Estrogen use was positively
associated with high density lipoprotein cholesterol and was inversel
y associated with body mass index. Nonsmokers, women who exercised at
least once per week, and women who reported having their cholesterol c
hecked in the past year were more likely to use estrogen. These findin
gs suggest that estrogen users have a more healthy profile than do non
users. In addition, the prevalence of postmenopausal estrogen use appe
ars to be substantially lower in women with natural versus surgical me
nopause throughout the period studied.