Hm. Klein et Rw. Gunther, DOUBLE-CONTRAST SMALL-BOWEL FOLLOW-THROUGH WITH AN ACID-RESISTANT EFFERVESCENT AGENT, Investigative radiology, 28(7), 1993, pp. 581-585
RATIONALE AND OBJECTIVES. A new technique was developed to achieve dou
ble contrast examinations in the small bowel without intubation. METHO
DS. Effervescent granules and tablets were coated with an acid-resista
nt acrylic lacquer to provide selective enteric gas release. The coati
ng thickness was 15% of dry weight for the granules and 1 to 4.5 mg/cm
2 for the tablets. Fifty patients were examined using the method in a
controlled study. All examinations were reviewed by two radiologists u
sing a three-step quality score. The results were compared to 20 enter
oclysis examinations. RESULTS. Image quality was better for the coated
tablets compared with the granules (P < .01). The double-contrast sma
ll bowel follow-through (DC-SBFT) provided a better quality examinatio
n in the terminal small bowel than in the jejunum. Enteroclysis yielde
d better results for the jejunum, but was not superior in the terminal
ileum. Average time of fluoroscopy was 477 seconds for the DC-SBFT (n
= 50) compared with 952 seconds for patients receiving enteroclysis (
n = 528). No side effects or adverse reactions occurred due to contras
t media application. CONCLUSIONS. The results of this new method are p
reliminary, yet promising. For young patients and certain indications
it may provide a less invasive alternative to enteroclysis.