DEHYDROOLIGOPEPTIDES .14. CONVENIENT COUPLING OF N-CARBOXY-ALPHA-DEHYDROAMINO ACID ANHYDRIDE WITH BOTH AMINE AND CARBOXYL COMPONENTS

Authors
SHIN C HONDA S MOROOKA K YONEZAWA Y
Citation
C. Shin et al., DEHYDROOLIGOPEPTIDES .14. CONVENIENT COUPLING OF N-CARBOXY-ALPHA-DEHYDROAMINO ACID ANHYDRIDE WITH BOTH AMINE AND CARBOXYL COMPONENTS, Bulletin of the Chemical Society of Japan, 66(6), 1993, pp. 1844-1846
Citations number
8
Categorie Soggetti
Chemistry
Journal title
Bulletin of the Chemical Society of Japan → ACNP
ISSN journal
00092673
Volume
66
Issue
6
Year of publication
1993
Pages
1844 - 1846
Database
ISI
SICI code
0009-2673(1993)66:6<1844:D.CCON>2.0.ZU;2-F
Abstract
In order to further develop and expand the usefulness of N-carboxy-alp ha-dehydroamino acid anhydride (DELTANCA), the optimum conditions of t he acylation of DELTANCA with N-protected alpha-amino acids (AA) were thoroughly examined. Furthermore, various kinds of AA or dipeptides as a C-component were utilized in the acylation of DELTANCA, followed by condensation with an AA methyl ester as an N-component.