A SIMPLE METHOD FOR SYNTHESIS OF 4-DIMETHYLAMINO-2,6-DIMETHYL-5-PHENYLPYRIMIDINES

Citation
W. Zielinski et M. Mazik, A SIMPLE METHOD FOR SYNTHESIS OF 4-DIMETHYLAMINO-2,6-DIMETHYL-5-PHENYLPYRIMIDINES, Heterocycles, 36(7), 1993, pp. 1521-1528
Citations number
16
Categorie Soggetti
Chemistry Inorganic & Nuclear
Journal title
ISSN journal
03855414
Volume
36
Issue
7
Year of publication
1993
Pages
1521 - 1528
Database
ISI
SICI code
0385-5414(1993)36:7<1521:ASMFSO>2.0.ZU;2-B
Abstract
The reaction of N-(1-methyl-2-phenylvinyl)acetimidoyl chloride and its derivatives substituted at the benzene ring with N,N-dimethylcyanamid e was studied. At the first stage, linear products like -3,5-dimethyl- 6-phenyl-2,4-diaza-1,3,5-hexatrienes were obtained. They underwent cyc lization to 4-dimethylamino-2,6-dimethyl-5-phenylpyrimidines in alkali ne medium at elevated temperature.