NOVEL METHOD FOR REDUCTIVE CLEAVAGE OF TRITERPENOID LACTONES WITH LITHIUM IN ETHYLENEDIAMINE

Authors
PRADHAN BP CHAKRABORTY DK ROY A
Citation
Bp. Pradhan et al., NOVEL METHOD FOR REDUCTIVE CLEAVAGE OF TRITERPENOID LACTONES WITH LITHIUM IN ETHYLENEDIAMINE, Indian journal of chemistry. Sect. B: organic chemistry, including medical chemistry, 32(7), 1993, pp. 721-725
Citations number
11
Categorie Soggetti
Chemistry Inorganic & Nuclear
Journal title
Indian journal of chemistry. Sect. B: organic chemistry, including medical chemistry → ACNP
ISSN journal
03764699
Volume
32
Issue
7
Year of publication
1993
Pages
721 - 725
Database
ISI
SICI code
0376-4699(1993)32:7<721:NMFRCO>2.0.ZU;2-0
Abstract
Sterically hindered gamma-lactones furnish mainly the saturated carbox ylic acids whereas delta-lactones with less hindrance yield the diols in higher percentage compared to the acids. Epsilon-Lactones,however, furnish the diols exclusively. The reduction is drastic and effective when other methods fail.