Sm. Guo et al., SERIAL ANALYSIS OF PLASMA-LIPIDS AND LIPOPROTEINS FROM INDIVIDUALS 9-21 Y OF AGE, The American journal of clinical nutrition, 58(1), 1993, pp. 61-67
Total cholesterol (TC) and low-density- (LDL-C) and high-density-lipop
rotein cholesterol (HDL-C) concentrations were recorded annually from
9 to 21 y of age to study tracking and predictive values for adulthood
lipid concentrations associated with cardiovascular disease. The trac
king coefficients for TC and LDL-C were congruent-to 0.7 for 4-, 6-, a
nd 12-y intervals, indicating good predictive value at ages 9-11 y for
risk of elevated concentrations at ages 19-21 y. Tracking of HDL-C wa
s less marked but the patterns were similar. The risk ratios for high
concentrations at 19-21 y were 3.8 for TC, 2.6 for LDL-C, and 4 for HD
L-C for 9-y-olds with values of 5.17 mmol/L for TC, 3.36 mmol/L for LD
L-C, and 0.90 mmol/L for HDL-C, relative to 9-y-olds with values of 4.
65 mmol/L for TC, 2.84 mmol/L for LDL-C, and 1.29 mmol/L for HDL-C.