Wa. Boisvert et al., PREVALENCE OF RIBOFLAVIN DEFICIENCY AMONG GUATEMALAN ELDERLY PEOPLE AND ITS RELATIONSHIP TO MILK INTAKE, The American journal of clinical nutrition, 58(1), 1993, pp. 85-90
Six groups of elderly subjects from central Guatemala were assessed fo
r riboflavin status by using the erythrocyte glutathione reductase act
ivity coefficient (EGRAC). The prevalence of riboflavin deficiency ran
ged from 50% to 76% among the free-living rural elderly subjects. Milk
intake data that were collected from some of the subjects showed a si
gnificant correlation (P < 0.0001) between frequency of milk intake an
d riboflavin status. In a short-term riboflavin supplementation experi
ment in which nine riboflavin-deficient subjects were given 10 mg ribo
flavin/d for 3 d, all the subjects' EGRACs were normalized by the supp
lementation. However, they returned to a state of deficiency within 2
wk while consuming their usual diets without supplementation. It appea
rs that the high prevalence of riboflavin deficiency in elderly Guatem
alan people is caused by inadequate intake of riboflavin-rich foods su
ch as dairy products, and that sufficient amounts of riboflavin need t
o be ingested regularly to maintain satisfactory riboflavin status.