J. Rankins et al., UNDERNUTRITION AND VITAMIN-A-DEFICIENCY IN THE DEPARTMENT-OF-LINGUERE, LOUGA REGION OF SENEGAL, The American journal of clinical nutrition, 58(1), 1993, pp. 91-97
Anthropometric measurements were taken on 281 toddlers (24-48 mo old)
in Linguere, Senegal, to determine the prevalence of undernutrition. B
lood samples collected from 271 of the toddlers were analyzed for reti
nol and carotenoids by HPLC. According to the National Center for Heal
th Statistics reference values 30.2% of the population was undernouris
hed. Serum retinol values were below the lower limit of the normal ran
ge in 71.5% of the children; 7.4% of this group had concentrations < 0
.35 mumol/L, placing them at risk for xerophthalmia. Only 3% of the po
pulation had serum retinol values greater-than-or-equal-to 1.0 mumol/L
. Serum carotenoids were low (< 0.70 mumol/L) in 55% of the children.
Retinol-binding protein values were low and measurable concentrations
of retinyl palmitate were detectable in only 17% of the children. Unde
rnutrition and poor vitamin A status were found to exist at a concentr
ation that would endanger health.