RECURRENT ENDOMETRIAL ADENOCARCINOMA AFTER SURGERY ALONE - PROGNOSTICFACTORS AND TREATMENT

Twenty-six patients with a local and/or regional relapse of a previous ly surgically treated adenocarcinoma of the endometrium were referred to the Dr. Daniel den Hoed Cancer Center (DDHCC) in Rotterdam, The Net herlands between 1965 and 1985 for external radiotherapy (ERT) and/or brachytherapy (BT). The 5-year overall survival was 44%. Tumour volume seemed to be an important prognostic factor in locoregional control; 1 out of 17 patients with tumour sizes smaller than or equal to 4 cm r elapsed locoregionally, while in 3 out of 9 patients with tumour sizes of more than 4 cm a locoregional recurrence developed. Another import ant finding is the impact of RT on treatment outcome: none of the 16 p atients treated with a combination of ERT and BT failed locoregionally , while 4 out of 10 patients treated with either ERT or BT relapsed.