EFFECT OF L-TYPE CALCIUM-CHANNEL MODULATORS ON STIMULANT-INDUCED HYPERACTIVITY

Authors
MOORE NA REES G SANGER G AWERE S
Citation
Na. Moore et al., EFFECT OF L-TYPE CALCIUM-CHANNEL MODULATORS ON STIMULANT-INDUCED HYPERACTIVITY, Neuropharmacology, 32(7), 1993, pp. 719-720
Citations number
6
Categorie Soggetti
Pharmacology & Pharmacy",Neurosciences
Journal title
Neuropharmacology → ACNP
ISSN journal
00283908
Volume
32
Issue
7
Year of publication
1993
Pages
719 - 720
Database
ISI
SICI code
0028-3908(1993)32:7<719:EOLCMO>2.0.ZU;2-Q
Abstract
The present study investigated the effect of L-type calcium channel mo dulators on stimulant-induced locomotor activity. The L-channel activa tor, (+/-)BayK8644, produced a marked, long-lasting enhancement of coc aine-induced activity, while having no effect on amphetamine hyperacti vity. Nicardipine reduced cocaine hyperactivity but had no effect on t he amphetamine response.