MOLECULAR ACTION OF THE TYPE-1 RIBOSOME-INACTIVATING PROTEIN SAPORIN-5 ON VICIA-SATIVA RIBOSOMES

Authors
IGLESIAS R ARIAS FJ ROJO MA ESCARMIS C FERRERAS JM GIRBES T
Citation
R. Iglesias et al., MOLECULAR ACTION OF THE TYPE-1 RIBOSOME-INACTIVATING PROTEIN SAPORIN-5 ON VICIA-SATIVA RIBOSOMES, FEBS letters, 325(3), 1993, pp. 291-294
Citations number
24
Categorie Soggetti
Biophysics,Biology
Journal title
FEBS letters → ACNP
ISSN journal
00145793
Volume
325
Issue
3
Year of publication
1993
Pages
291 - 294
Database
ISI
SICI code
0014-5793(1993)325:3<291:MAOTTR>2.0.ZU;2-O
Abstract
The type 1 ribosome-inactivating protein (RIP) saporin 5 isolated from seeds of Saponaria officinalis L. strongly inhibited translation carr ied out by Vicia sativa L. purified ribosomes. The toxin multidepurina ted V. sativa rRNA, which upon treatment with acid aniline releases se veral RNA fragments including an RNA fragment of approximately 370 nuc leotides the 5'-end sequence of which was 5'-GAGGAACG-3'.