SYNTHESIS AND SOME REACTIONS OF 4[(6'METHENYL-INDOL-5'Y1)-METHYLENE]-2-PHENYLOXAZOLIN-5-ONE FOR PHARMACOLOGICAL EVALUATION

Authors
ABDELRAHMAN AH KANDEEL EM ABDELRAZIK EA ELGHAMRY IA
Citation
Ah. Abdelrahman et al., SYNTHESIS AND SOME REACTIONS OF 4[(6'METHENYL-INDOL-5'Y1)-METHYLENE]-2-PHENYLOXAZOLIN-5-ONE FOR PHARMACOLOGICAL EVALUATION, Anales de quimica, 89(2), 1993, pp. 237-241
Citations number
12
Categorie Soggetti
Chemistry
Journal title
Anales de quimica → ACNP
ISSN journal
11302283
Volume
89
Issue
2
Year of publication
1993
Pages
237 - 241
Database
ISI
SICI code
1130-2283(1993)89:2<237:SASRO4>2.0.ZU;2-H
Abstract
Condensation of 5-formyl-6-methoxy-2,3-diphenylindole with hippuric ac id gives the tide compound (1) which subsequently is reacted with hydr azine hydrate, hydroxylamine hydrochloride, different amines, o-phenyl ene-diamine, malononitrile, ethyl cyanoacetate, sodium hydroxide, and sodium methoxide yielding thus compounds 2-18 of expected biological a ctivities. Their structural assignments are based on elemental analyse s and spectral data.