M. Hakala et al., RHEUMATOID-ARTHRITIS AS A CAUSE OF CARDIAC COMPRESSION - FAVORABLE LONG-TERM OUTCOME OF PERICARDIECTOMY, Clinical rheumatology, 12(2), 1993, pp. 199-203
In order to clarify the significance of rheumatoid arthritis (RA) as a
cause of cardiac compression, we scrutinized pericardiectomy riles of
47 patients over a ten-year period at two university hospitals in Fin
land. Five patients with RA were found. All the patients with RA were
men with seropositive disease and subcutaneous rheumatoid nodules. Two
of the patients had pulmonary fibrosis, one had cutaneous vasculitis
and three had had rheumatoid pleurisy. There was a mean delay of 10 mo
nths from the first cardiac symptom to the diagnosis of cardiac compre
ssion, the most common misdiagnosis being primarily a liver disease. O
n the basis of clinical and operative data, four out of the rive patie
nts had constrictive pericarditis and one had an effusive-constrictive
form of the disease. The histopathological findings in all cases were
consistent with chronic fibrosing pericarditis. A follow-up of seven
to seventeen years of four patients has not revealed any signs of recu
rrent pericardial disease. Our results demonstrate that RA is an impor
tant aetiological factor for cardiac compression. The long-term outcom
e of this manifestation seems to be good after pericardiectomy.