A. Herraez et al., IMMUNOLOGICAL RELATIONSHIP AMONG RAT ERYTHROCYTE-MEMBRANE SIALOGLYCOPROTEINS AND WITH HUMAN GLYCOPHORINS, International Journal of Biochemistry, 25(7), 1993, pp. 1009-1014
1. Specific antibodies against a whole preparation of glycophorins fro
m rat erythrocyte membrane and against its most prominent component (3
2 kDa) were prepared. 2. Both antisera and the respective affinity-pur
ified antibodies recognize the 74, 32 and 25 kDa components of rat gly
cophorins; therefore, a close antigenic relationship between them can
be inferred. 3. On the other hand, a cross-reaction with human glycoph
orin A (both MM- and NN-type) is observed for both antisera. 4. This s
uggests the existence of epitopes common to human and rat glycophorins
.