IMMUNOLOGICAL RELATIONSHIP AMONG RAT ERYTHROCYTE-MEMBRANE SIALOGLYCOPROTEINS AND WITH HUMAN GLYCOPHORINS

Citation
A. Herraez et al., IMMUNOLOGICAL RELATIONSHIP AMONG RAT ERYTHROCYTE-MEMBRANE SIALOGLYCOPROTEINS AND WITH HUMAN GLYCOPHORINS, International Journal of Biochemistry, 25(7), 1993, pp. 1009-1014
Citations number
24
Categorie Soggetti
Biology
ISSN journal
0020711X
Volume
25
Issue
7
Year of publication
1993
Pages
1009 - 1014
Database
ISI
SICI code
0020-711X(1993)25:7<1009:IRARES>2.0.ZU;2-B
Abstract
1. Specific antibodies against a whole preparation of glycophorins fro m rat erythrocyte membrane and against its most prominent component (3 2 kDa) were prepared. 2. Both antisera and the respective affinity-pur ified antibodies recognize the 74, 32 and 25 kDa components of rat gly cophorins; therefore, a close antigenic relationship between them can be inferred. 3. On the other hand, a cross-reaction with human glycoph orin A (both MM- and NN-type) is observed for both antisera. 4. This s uggests the existence of epitopes common to human and rat glycophorins .