PERCUTANEOUS MITOMYCIN-C PERFUSION OF BILATERAL URETERAL CARCINOMA IN-SITU

We treated a 61-year-old patient with a diagnosis of bilateral uretera l carcinoma in situ with percutaneous perfusions of mitomycin C. After 16 sessions of mitomycin C therapy instilled through bilateral nephro stomy tubes, the urine cytology results became negative for malignancy . Bilateral ureteroscopy and cold-cup punch biopsies of the ureter rev ealed no evidence of disease. The patient did not experience side effe cts. He has remained free of disease during a 12-month follow-up perio d. Percutaneous perfusion of mitomycin C appears to be one of the effe ctive and safe treatments for the carcinoma in situ of the upper urina ry tract.