PROTECTION AGAINST RH D-HEMOLYTIC DISEASE OF THE NEWBORN BY A DIMINISHED TRANSPORT OF MATERNAL IGG TO THE FETUS

Authors
DOOREN MC ENGELFRIET CP
Citation
Mc. Dooren et Cp. Engelfriet, PROTECTION AGAINST RH D-HEMOLYTIC DISEASE OF THE NEWBORN BY A DIMINISHED TRANSPORT OF MATERNAL IGG TO THE FETUS, Vox sanguinis, 65(1), 1993, pp. 59-61
Citations number
7
Categorie Soggetti
Hematology
Journal title
Vox sanguinis → ACNP
ISSN journal
00429007
Volume
65
Issue
1
Year of publication
1993
Pages
59 - 61
Database
ISI
SICI code
0042-9007(1993)65:1<59:PARDDO>2.0.ZU;2-J
Abstract
IgG present in the circulation of newborn infants is predominantly of maternal origin. In cases of severe Rh D alloimmunization, the materna l anti-D antibodies may lead to Rh D-haemolytic disease of the newborn . However, an impaired placental transport of maternal IgG could be as sociated with the protection of the fetus/newborn against haemolytic d isease as shown in this case report.