A REVIEW OF 28 YEARS OF TREATING ADVANCED OVARIAN-CANCER

The treatment of advanced ovarian cancer at the Women's Clinic of the University of Pecs, Hungary, during 1962-1989 is described in a histor ical review. The results of 82 patients treated with cyclophosphamide (C), 83 patients treated with non-cisplatin (CMV or CAV) and 41 patien ts treated with a cisplatin (CAP) combinations were compared. Progress ion-free survival was better with the CMV or CAV than with C. CAP was associated with significantly better remission rates, survival and pro gression-free survival than the other treatments. Analysis supports th e prognostic importance of postsurgical residual tumour size. Consolid ation radiotherapy and maintenance or second line chemotherapy are rec ommended.