ON THE CELLS INHIBITING THE FORMATION OF STROMAL COC-F COLONIES IN BONE-MARROW CULTURES

Authors
GORSKAYA YF SHUKLINA YY
Citation
Yf. Gorskaya et Yy. Shuklina, ON THE CELLS INHIBITING THE FORMATION OF STROMAL COC-F COLONIES IN BONE-MARROW CULTURES, Gematologia i transfuziologia, 37(7-8), 1992, pp. 10-12
Citations number
NO
Categorie Soggetti
Hematology
Journal title
Gematologia i transfuziologia → ACNP
ISSN journal
02345730
Volume
37
Issue
7-8
Year of publication
1992
Pages
10 - 12
Database
ISI
SICI code
0234-5730(1992)37:7-8<10:OTCITF>2.0.ZU;2-Q
Abstract
The presence of embryonal calf serum (ECS) in the cultural medium in n ecessary for the inhibition of CFU(f) colony growth in rabbit bone mar row cultures by hemopoietic and lymphoid cells. The inhibitory effect is sharply decreased when, besides ECS, the cultural medium contains s era autologous for the reacting cells (rabbit serum), and sera of matu re animals of some other species (mouse, rat). The inhibitory activity depends on soluble factors penetrating milliporous filters. It has be en revealed that the cells inhibiting CFU(f) growth have the marker F4 80. T-cells, probably, are not involved in the effect studied.