The results of the clinico-laboratory analysis conducted in 69 patient
s with varying forms of acute purulent surgical infections have shown
that the therapeutic plasmapheresis is attended by the improvement of
the disease clinical picture, and attenuation of endotoxicosis by day
3 after the perfusion. Indications and contraindications for plasmaphe
resis in critical patients are considered, the causes of unsuccessful
plasmapheresis procedures are analyzed, the ways for the improvement o
f this operation are outlined.